22 July 2014
There’s currently no cure for retinitis pigmentosa (RP), a group of inherited eye diseases that impair the retina’s ability to respond to light, resulting in gradual loss of vision. But now, researchers have used stem cells to develop a promising experimental treatment. First they reprogrammed skin cells from RP patients into stem cells to make patient-specific retinal cells for closer inspection. They found that mutations in a gene called MFRP disrupt the production of actin (red), a protein that provides scaffolding for retinal cells. When this structure doesn’t form properly (left), retinal cells don’t work very well. But when the team used a virus to smuggle in a working copy of MFRP, the structure was restored (right). And in mice with an RP-like condition, the treatment slowly improved vision. It’s early days yet but these results show how patient-specific stem cells can kick start the development of tailor-made therapies.
Written by Daniel Cossins
Image by Stephen Tsang and colleagues
Columbia University Medical Center, USA
Originally published under a Creative Commons Licence (BY 4.0)
Research published in Molecular Therapy, July 2014
You can also follow BPoD on Twitter and Facebook
If it all plays out as expected and budgeted, astronomers of the 2020s will be swimming in petabytes of data streaming from space and the ground. Herewith a report card on the future of big-time stargazing.
More Eyes on the Skies
A new report (detailed here) from Columbia University details how climate change may effect Central Park. The report says rising temperatures will be hard on our trees—especially the young and old—and on the organisms (both animal and vegetal) that live in our man made bodies of water, and it may make caring for our famous lawns ever more challenging.
But, there is an upside. Central Park is actually a useful tool in mitigating the effects of climate change. As long as we, the Central Park Conservancy, continue to support the Park’s biodiversity and keep our ecosystem healthy (a task we are deeply committed to), then the Park will continue to “increase its resilience to climate change, and make it a suitable habitat for more plants and animals.”
(via Studying climate change in Central Park | New York)
#israel #Palestine #war crimes #bombs
(Source: blvcknvy, via clockworkprincess)
THIS IS IMPORTANT, PLEASE DON’T FEED THESE TREATS TO YOUR DOGS
My mom bought these recently and they have made both of my dogs really sick. She later saw an article online about duck and sweet potato treats made in China(these fit the description) killing dogs and the FDA is doing nothing about it. Apparently over the last few years 600 young, healthy dogs have died after eating these treats and I don’t want anymore to suffer or be killed so please spread the word and don’t let your dogs have these!
This is VERY important! A lot of these animal treats made in China are killing dogs and cats. It’s not that the FDA isn’t doing anything about it, it’s simply that they don’t know why it’s happening.
They are conducting investigation after investigation, but the ingredients used in the food killing dogs (and 10 cats) is used in many different brands and companies that have been shipped, all from overseas. At this rate, a total recall and knowledge of where it’s coming from has proven very difficult. Just recalling one brand in particular will not solve the problem. Please conduct a thorough search about any brand of treats that have been made in China should you pick them up for your pet before you feed it to them. If all else fails, just buy local.
EDIT: Here is a list of food that has been recalled (so far) with more information
Please PLEASE be aware that this isn’t only happening to dogs, but some cat treats, too!
This may save lives!!
This Is How The Media Chooses To Profile A Female Activist
Cecily McMillan, the 25-year-old Occupy Wall Street activist who was jailed for elbowing a police officer during a protest, returned to court on Thursday, where a cadre of hard-hitting journalists greeted her with questions about her courtroom attire.
“My editor told me to ask who you’re wearing,” a photographer was spotted eagerly asking McMillan, according to The Village Voice.
McMillan, who was earlier this month released from Rikers Island — one of the country’s most notoriously violent jails — explained that although she was free, she no longer felt safe in New York “because I was sexually assaulted and then put in jail for it," according to the Voice. McMillan has alleged from the start that the officer involved in her assault case forcibly grabbed her breast from behind during the protest; after elbowing him, she was promptly arrested and put in jail.
Upon hearing her explanation Thursday, a Post reporter responded, “Well, you look fabulous! But you should eat more.”
The interactions resulted in a blatantly sexist portrayal of McMillan sprinkled with mocking details about her fashion choices — all of which fail to mention that she was asked such questions by the press.
The Daily News went straight to the sartorial details with the headline, “Occupy Wall Street protester wears Calvin Klein to court.”
The Post’s own coverage included a previously dated photo of an emotional McMillan with the caption, “McMillan cries in court in May after being given an outfit she had already worn." The paper led with the headline "Rikers Island: The new way to lose weight.”
Rikers is currently at the center of damning allegations of officer abuse, contraband smuggling by officers, regular beatings of the mentally ill, and corruption.
McMillan has been using her newfound freedom to speak out against the treatment of inmates at Rikers — a cause that is essentially being buried for more important notes on her outfit choices. Well done, New York media!